We examine whether and how a country’s centrality in global value chains (GVCs) is dependent upon the extent to which its regulatory regime differs from the global norm, using country and sector-level data from OECD and UNCTAD. We find that the more similar a country’s regulatory regime is to global standards the more likely the country is to play a dominant role in GVCs. Our findings suggest that a country could enhance its centrality in GVCs by harmonising a set of technical regulations to the global standards.